Yes, the Beelink system you listed above would be compatible with macOS.
NootedRed.kext will get the AMD Integrated GPU working in macOS.
Storage would be down to you, as the system can accept 2 x NVME drives with a combined maximum storage capacity of 8TB (2 x 4TB).
Specification for built-in storage. 500GB is the standard drive size.
Plus you have the option of using external enclosures with additional storage if required, via USB3, Type-C or Ethernet/Network.
Built-in WiFi & Bluetooth is based on Intel AX200 chipset, so this will be supported by IntelWireless kexts etc.
The dual Ethernet ports are reported as 1GB, but I can't find any information on which chip is used by the controller, so no idea which kext(s) would be required for them to work in macOS.
I have a similar spec Gen Machine REN 7000 mini PC system that can run macOS and Windows 11 (each OS on a separate NVME drive). My experience with the Gen Machine system can be found in the link below.
I am just confirming that I have installed macOS Ventura on this Gen Machine Ren 7000 series mini PC, after a few component changes to the stock system.
The component changes included:
Replacement of the Kingspec NX series 512GB NVMe drive with a Crucial P3 Plus 1TB NVMe drive, for use as macOS boot drive.
Replacement of the Realtek RTL8852B WiFi/BT card with an Intel AX200NGW WiFi/BT card.
Addition of Integral 512GB M.2 NVMe 2242 PCIe Gen3 x4 SSD, for use as Windows boot drive.
Addition of DDDR4 8GB 3200MHz RAM (spare from defunct laptop) to go with existing 16GB module...
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