I think it works best with a MacPro6,1/7,1 SMBIOS. It worked with my two older FX based AMD systems.
Intel WiFi and Bluetooth modules, which I assume the OP is using, when booting Monterey requires the following kexts:
- Airportitlwm.kext - for use with native Apple WiFi app
- IntelBluetoothFirmware.kext - to fix firmware issues
- BlueToolFixup.kext - fix BT issues in Monterey
You should not use the IntelBluetoothInjector.kext when booting Monterey. As the changes Apple made to the Bluetooth stack in Monterey mean this kext won't work. It should only be used if you are booting Big Sur or older versions of macOS. You need to set the MaxKernel entry for the kext to 20.99.99 (Big Sur) in the config.plist to prevent it loading in Monterey, if it has already been added to your OC setup.
The three kexts your system needs when booting Monterey are attached below.