Probably. Depends on how you hook it up.
Anyhow, you will probably have to install to an external USB (hard)drive. People have reported issues with the installer not seeing the internal HDD on laptops.
Should be able to just follow one of the guides over at https://kb.amd-osx.com
to set it up. Remember that you are running a very unsupported configuration, so GPU performance will suffer badly.
Hilda - Workstation
CPU - AMD Ryzen 2600x
GPU - Nvidia GTX 1060 6GB
RAM - 16GB DDR4
MOBO - MSI B350 Tomahawk
NIC1 - RTL8111
NIC2 - RTL8169sc
Audio - ALC887
Storage - 240GB NVMe, 1TB HDD, 2TB HDD, 240GB SSD
@NoOne#8086 on Discord!