So, I have clean install Catalina 10.15.5, but the problem is still there. Cursor is lagging when it came across text (usually in Telegram like in the video above), and lagging when I do drag and drop links in Mail application.
I also noticed, that cursor sometimes is slowing down, and when it happens my sound is crackling a little. When I call someone (Skype for example) my mic is also crackling (and my partner hear the sound like you unplug and plug back 3.5 jack).
I tried to change boot args, tried to remove some kexts, tried to boot without WEG, tried to make USB map, tried to replace mouse, but nothing did help. It's only better, when I unplug my 4k monitor and use only one 1080p, but the problem don't want to go away completely.
Here the full specs:
CPU: Ryzen 5 3600
GPU: Sapphire RX 580 PULSE
Motherboard: ASUS B450 PRIME PLUS
RAM: Corsair LPX 16 GB 3200Mhz
ADATA XPD NVMe 250 GB and SSD Samsung EVO 500 GB (tried to install Catalina on both)
Dual monitor setup: 4K@60 and 1080p@144
Do you have any updates
@Virgo ? I hope you found a solution